卢健（邮箱lujian1993@njucm.edu.cn）, 博士，副教授，硕士生研究生导师，现任职3044am永利集团欢迎您生理学系。

主要从事神经退行性疾病药理学研究，相关研究成果发表SCI学术论文10余篇 ，授权专利2项，参译著作《阿尔兹海默病的系统生物学》1部。

代表性研究论文 

1.Jian Lu, Anxu He, Zhuoying Jin, Meng Zhang, Zhongxin Li, Lin Ma, Hongming Jin, Jiaying Wang, Xu Shen. Desloratadine alleviates ALS-like pathology in hSOD1G93A mice via targeting 5HTR2A on activated spinal astrocytes. Acta Pharmacologica Sinica, 2024, DOI: 10.1038/s41401-023-01223-2 .

2.Jian Lu, Chuzhao Zhang, Jianlu Lv, Xialin Zhu, Xingwu Jiang, Weiqiang Lu, Yin Lu, Zongxiang Tang, Jiaying Wang, Xu Shen. Antiallergic drug desloratadine as a selective antagonist of 5HT2A receptor ameliorates pathology of Alzheimer's disease model mice by improving microglial dysfunction. Aging Cell, 2021, 20(1), e13286.

3.Ruifang Nie, Jian Lu, Xingyi Shen, Xingnan Ouyang, Danyang Zhu, Rui Xu, Yujie Huang, Tong Zhao, Xuejian Zhao, Yin Lu, Minyi Qian, Jiaying Wang, Xu Shen. Ipriflavone as a non-steroidal glucocorticoid receptor antagonist ameliorates diabetic cognitive in mice. Aging cell, 2022, 21(3), e13572. 

4.Danyang Zhu, Jian Lu, Rui Xu, Juanzhen Yang, Xiangrui Meng, Xingnan Ouyang, Qiuying Yan, Ruifang Nie, Tong Zhao, Yidi Chen, Yin Lu, Yinan Zhang, Wenjun Li, Xu Shen. FX5, a non-steroidal glucocorticoid receptor antagonist, ameliorates diabetic cognitive impairment in mice. Acta Pharmacologica Sinica, 2022, 43(10), 2495–2510. 

5.Xiaokang Li, Jian Lu, Yixiang Xu, Jiaying Wang, Xiaoxia Qiu, Lei Fan, Baoli Li, Wenwen Liu, Fei Mao, Jin Zhu, Xu Shen, Jian Li. Discovery of nitazoxanide-based derivatives as autophagy activators for the treatment of Alzheimer's disease. Acta Pharmaceutica SinicaB, 2020, 10(4), 646-666.